Welcome to Our Lung Cancer DataBase !
Lung cancer is the most common cause of cancer-related death in men and the second most common in women, with a 5-year survival rate approximately 15%. It is responsible for 1.3 million deaths worldwide annually. Although Tabacco smoking is believed to contribute to approx. 90% of lung cancer cases, epigenetic or genetic changes occurred in cells directly promote the lung cancer initiation, progression and metastasis. Compilation of the lung cancer gene information will no doubt lead to a better understanding of this most deadly disease.
"We have collected the information of genes and miRNAs with the experimental evidences involved in the different stages of lung cancer progression through text mining and we also have incorporated the transcription factor binding motifs, the promoters, the SNP sites for each genes, as well as related clinical information and experiment evidences. We hope that those information will improve our knowledge about lung cancerigenesis and potentially contribute to the development of novel therapeutic strategies ."
Please cite :Lishan Wang, Yuanyuan Xiong, Yihua Sun, Zhaoyuan Fang, Li Li, Hongbin Ji,and Tieliu Shi.HLungDB: an integrated database of human lung cancer researchNucleic Acids Research, doi:10.1093/nar/gkp945