Related Signaling interaction pathway:

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IL12 signaling mediated by STAT4

Related component ;click for the further info from NCBI
STAT4 (dimer)ERMIL18R1IL18RbetaIL18R
c-JunIL18IL13JunCBP
IL2R alphaJNK1-2JNK1-2-activeAP-1NFAT1-c-4
IL2IRF1T-betTGFB1IFN-gamma
TCRCD3MHC IICD4Calcineurin A alpha-beta B1
STAT3 (dimer )Perforin 1PIASxBetaB7 familyCD28

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
207747 STAT4 (dimer)   transcription agent nucleus active 10097133    
207731 IL18R1   modification input integral to membrane 11046021    
207750 STAT4 (dimer)   natural killer cell mediated cytotoxicity agent nucleus active 8700208    
207735 STAT4 (dimer)   modification input nucleus active 11801649    
207744 STAT4 (dimer)   transcription agent nucleus active 15728489    
207741 STAT4 (dimer)   modification input nucleus active 14660657    
207732 IL18   modification input 9325300    
207742 STAT4 (dimer)  Jun  CBP   transcription agent nucleus active 14660657    
207733 JNK1-2   modification input 11801649    
207749 AP-1  NFAT1-c-4   transcription agent nucleus active 16365415    
207740 STAT4 (dimer)   transcription agent nucleus active 10037767  10358173    
207726 STAT4 (dimer)   transcription agent nucleus active 7737303  11786644  11207258  10946290  2504877  12213961  8700209    
207734 c-Jun   modification input nucleus 11801649    
207743 TCR  CD3  MHC II  CD4   transcription agent integral to membrane active 11786644  16641133    
207736 STAT4 (dimer)  c-Jun   transcription agent nucleus active 11786644  11801649  9558063    
207739 STAT3 (dimer )   transcription agent active 11786644  15522880    
207727 STAT4 (dimer)   T-helper 1 cell differentiation agent nucleus active 7722452  8700208  12213961    
207730 STAT4 (dimer)   transcription agent nucleus active 11466347    
207729 STAT4 (dimer)   transcription agent nucleus active 11466347    
207728 STAT4 (dimer)   T-helper 2 cell differentiation inhibitor nucleus active 8700209    
207746 STAT4 (dimer)   transcription agent nucleus active 12372421    
207738 STAT4 (dimer)  PIASxBeta   negative regulation of transcription agent nucleus inactive   
207745 IFN-gamma   apoptosis inhibitor extracellular region 15728489    
207748 STAT4 (dimer)   transcription agent nucleus active 11786644  12213961  10229825  8700209    
207737 STAT4 (dimer)   modification input nucleus active 12716907