Related Signaling interaction pathway:

Data buffering takes about 1 or more minute acording to the network size.



Paxillin-independent events mediated by a4b1 and a4b7

Related component ;click for the further info from NCBI
JAK2alpha4beta1 IntegrinEPOEPOR (dimer)
Rac1GTPVCAM1p130CasCRK
DOCK1CrkDock1FAK1Src
beta7 IntegrinMAdCAM1RhoARAC1GDP
PI-3KCRKLCBLPaxillinGIT1
ARF6CD44

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
207079 JAK2   modification input cytoplasm 12589802    
200503 Rac1  GTP   lamellipodium assembly agent active 12973357  12589802  11886862  12393875  18033240  15793570  15351743    
207072 alpha4  beta1 Integrin   modification input 16670268  1377605    
207075 p130Cas   modification input active 16227616    
207080 FAK1   modification input cytoplasm 8634433    
207073 Src   modification input 11238661  16227616    
207085 alpha4  beta7 Integrin  MAdCAM1   cell adhesion agent 10508262    
207074 p130Cas   modification input 16227616    
207084 alpha4  beta7 Integrin   modification input 9233649  9655832  7687523  7511642  10508262  8912000    
207081 FAK1   modification input cytoplasm 8634433    
207077 RAC1  GDP   modification input inactive 12589802  16227616  15793570    
207082 alpha4  beta7 Integrin   positive regulation of cell-cell adhesion input 9041197