Related Signaling interaction pathway:

Data buffering takes about 1 or more minute acording to the network size.



p53 pathway

Related component ;click for the further info from NCBI
p53 (tetramer)SET7p53PCAFUSP7
STRAPPRMT5DYRK2iASPPGsk3beta
p14ARFMDM2NEDD8FBXO11E4F1
UBCH5DNA-PKTIP60HAUSPDAXX
RASSF1ACbpp300SKP2RPL5
RPL11RPL23CSE1Lp53AIP1KAP1
ATMPIRH2PIN1WIP1MDM4
p38 alphac-AblCyclin G1PP2A-BprimeHIPK2
hMOFCHK1-2YY1CHK2COP1
ARF-BP1AKT1SET8JNK1-2-activeCDK2
Cyclin ACK1 familyATRSMYD2PKC delta

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
207054 p53 (tetramer)   modification input nucleus 15525938  17646389    
207019 p53   translocation input cytoplasm 17268548  10821866  12667443    
207018 p53 (tetramer)   modification input nucleus 17110336  9744860  9891054    
207020 p53   modification input mitochondrion 17268548    
207061 STRAP   modification input nucleus 19011621    
207048 p53 (tetramer)   modification input nucleus 17906639  17349958    
207027 p53 (tetramer)   subnet input nucleus   
207029 p53   autophagy input cytoplasm 18454141    
207016 p53   modification input nucleus   
207044 p53   modification input nucleus 14744935    
207025 p53 (tetramer)   subnet input nucleus   
207000 p14ARF   modification input 9724636  9529248  9878046  9529249    
207059 p53   modification input nucleus 17098746    
207017 p53 (tetramer)   modification input nucleus 17110336  9288740    
207062 p53 (tetramer)   modification input nucleus 19011621    
206994 p53   modification input nucleus 14671306  11340074  10734067  11713287    
207036 p53   modification input nucleus 9363941    
207041 p53   apoptosis agent nucleus 16757976    
207050 p53 (tetramer)   modification input nucleus 17534149  17189187  17189186    
207015 MDM2   modification input 18566590  16845383    
206998 MDM2  UBCH5   modification input nucleus 11715018    
207051 p53 (tetramer)   modification input nucleus 18485870    
207001 MDM2   modification input 15314173  12842086  15308643  14612427    
207032 p53 (tetramer)   transcription agent nucleus 11030628  17719542    
207057 p53   modification input nucleus 16107876    
207022 p53   proteasomal ubiquitin-dependent protein catabolic process input cytoplasm 11127820    
207060 STRAP   modification input cytoplasm 15448695    
206997 MDM2   modification input 9450543    
207065 p53   proteasomal ubiquitin-dependent protein catabolic process input nucleus 12654245    
207039 p53   modification input nucleus 12397361  12397362    
207058 p53   modification input nucleus 15242646    
207024 p53   subnet input mitochondrion   
207006 MDM2   modification input nucleus inactive 17936559    
207002 MDM4   proteasomal ubiquitin-dependent protein catabolic process input nucleus 12963717  16163388    
207045 p53   modification input nucleus 14671306  11340074  11713287  14654783    
206993 p53   proteasomal ubiquitin-dependent protein catabolic process input nucleus 9153395  19357310  14671306  19597489  11715018  11504915  11046142    
207040 p53 (tetramer)   modification input nucleus 10581258  17906639    
207005 MDM2   modification input 12110584    
207008 MDM2   modification input inactive 11983168    
207012 MDM2   modification input 11606419  15029243    
207007 Cyclin G1   modification input 11983168    
207026 p53 (tetramer)   subnet input nucleus   
207014 MDM2   proteasomal ubiquitin-dependent protein catabolic process input 15029243  17293853    
207035 p53   modification input nucleus 9733515  9733514    
207031 p53 (tetramer)   modification input nucleus 11740489  17906639  11780126    
207052 p53 (tetramer)   modification input nucleus 17534149  17189187    
207037 p53   modification input nucleus 10673501    
207013 MDM2   modification input 17293853    
206992 p53   modification input nucleus 9450543  9153395  14671306  15210108  9153396    
207046 MDM4   modification input 16163388    
207064 p53   proteasomal ubiquitin-dependent protein catabolic process input nucleus 15103385    
207067 p14ARF   modification input 15989956    
206995 MDM2  UBCH5   modification input 11715018  11504915    
207056 p53 (tetramer)   modification input nucleus 17707234    
207030 p53 (tetramer)   subnet input nucleus   
207038 p53   modification input nucleus 10581258  11283254  11078726    
207053 Cbp  p300   modification input nucleus 18243116    
207042 p53   modification input nucleus 10734067  10606744    
207003 MDM2   modification input 14654783    
207009 MDM2   modification input 11359766    
207055 p53 (tetramer)   modification input nucleus 17108971    
207004 MDM2   modification input 10611322  11331603    
207021 p53   modification input cytoplasm 11127820    
206999 MDM2  UBCH5   modification input 15210108    
206996 MDM2  UBCH5   translocation input 11715018  11504915    
207028 p53 (tetramer)   subnet input nucleus   
207066 p53   proteasomal ubiquitin-dependent protein catabolic process input nucleus 15989956    
207047 DYRK2   modification input cytoplasm 17349958    
207043 Gsk3beta   modification input inactive 14744935    
207049 p53 (tetramer)   modification input nucleus 17906639  16377624