Related Signaling interaction pathway:

Data buffering takes about 1 or more minute acording to the network size.



IL2 signaling events mediated by STAT5

Related component ;click for the further info from NCBI
STAT5 (dimer)-activeElf1IL2R alphaSP1Cyclin D2
IL2betagammaJAK1LCK
JAK3SHCGRB2SOS1GAB2
SHP2PI3KCyclin D3Cyclin ATNFB
MYCCDK6BCL2BCL-XFOXP3
Perforin 1FASLGIL4

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
206301 STAT5 (dimer)-active   transcription agent nucleus active 9104808  9121484  11485747  9395528    
206312 STAT5 (dimer)-active   transcription agent nucleus active 11160217  10072077    
206313 STAT5 (dimer)-active   transcription agent nucleus active 9390691  10072077    
206319 Cyclin A   G1/S transition of mitotic cell cycle agent 10072077    
206300 STAT5 (dimer)-active   transcription agent nucleus active 9541574    
206306 STAT5 (dimer)-active   activation-induced cell death of T cells inhibitor nucleus active 16757175    
206299 STAT5 (dimer)-active   transcription agent nucleus active 10679091    
206318 CDK6   G1/S transition of mitotic cell cycle agent 10072077    
206310 BCL2   activation-induced cell death of T cells inhibitor mitochondria 8617294    
206317 Cyclin D3   G1/S transition of mitotic cell cycle agent 10072077    
206315 STAT5 (dimer)-active   transcription agent nucleus active 10072077    
206316 Cyclin D2   G1/S transition of mitotic cell cycle agent 10072077    
206308 STAT5 (dimer)-active   transcription agent nucleus active 10679091  8617294    
206304 STAT5 (dimer)-active   transcription agent nucleus active 16645171  17182565    
206305 STAT5 (dimer)-active   CD4-positive CD25-positive alpha-beta regulatory T cell lineage commitment agent nucleus active 14607901  14500638  12196288    
206303 STAT5 (dimer)-active   transcription agent nucleus active 10544201    
203827 MYC   cell proliferation agent nucleus   
206314 STAT5 (dimer)-active   transcription agent nucleus active 10072077    
206311 BCL-X   activation-induced cell death of T cells inhibitor mitochondria 8617294    
206309 STAT5 (dimer)-active   transcription agent nucleus active 10514006    
206302 STAT5 (dimer)-active   transcription agent nucleus active 15004274  14614860    
206307 STAT5 (dimer)-active   transcription agent nucleus active 10679091  8617294