Related Signaling interaction pathway:

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Stabilization and expansion of the E-cadherin adherens junction

Related component ;click for the further info from NCBI
PIP5K1CE-cadherinCa2+beta cateninalpha catenin
p120 cateninalpha-Actininmyosin II complexROCK1Mena
Aquaporin-3Aquaporin-5SEC6SEC8Syntaxin-4
ARF6GTPGDPEphrin A1EPHA2
NCK1GIT1EPLINRhoAVASP
zyxinNezhaVinculinMyosin VIDIAPH1
EGFREGFIGF1IGF-1R heterotetramerKIF3C
LPPPLEKHA7HGFMETPI-4-5-P2
cortical actin cytoskeletonMGAT3PI-4-PABI1Sra1
Nap1exocystnectin-2(dimer)I-afadin

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
206121 PIP5K1C   modification input 17261850    
206115 alpha-Actinin   translocation input cytoplasm 7790378  18413140    
206096 myosin II complex   modification input inactive 16030252    
206095 Mena   actin cable formation agent cell-cell junction active 18413140  16371509  10660044    
206170 Aquaporin-3   translocation input Golgi apparatus 17635938    
206174 ARF6  GTP   modification input active 19193766    
206173 Ephrin A1  EPHA2   modification input cell-cell junction active 19193766    
206084 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   modification input cell-cell junction 18093941    
206097 myosin II complex   adherens junction organization agent cell-cell junction active 16030252    
206125 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   epithelial cell differentiation agent cell-cell junction 14704278    
206092 RhoA  GDP   modification input inactive 17646397  9182672  10980705    
206118 VASP   modification input 16613855    
206105 Nezha   adherens junction assembly agent cell-cell junction 19041755    
206098 myosin II complex   regulation of cell-cell adhesion agent cell-cell junction active 17646397    
206089 Vinculin   translocation input cytoplasm 17664339    
206108 DIAPH1   actin cable formation agent cell-cell junction active 17940061    
206177 EGFR   modification input integral to membrane 7962096  8660958  15057284    
206178 IGF1   modification input 15057284    
206103 KIF3C   translocation input 19041755    
206117 VASP   modification input 18413140  16613855    
206101 PLEKHA7   translocation input 19041755    
206179 HGF   modification input extracellular region 15057284    
206091 Vinculin   actin cytoskeleton organization agent cell-cell junction 17664339    
206114 zyxin   modification input cell-cell junction 18413140  10660044    
206123 PI-4-5-P2   adherens junction assembly agent cell-cell junction 17261850    
206087 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin  EPLIN  cortical actin cytoskeleton   adherens junction organization agent cell-cell junction 18093941    
206176 MGAT3   regulation of calcium-dependent cell-cell adhesion agent active 11024053    
206122 PI-4-P   modification input 17261850    
206104 KIF3C   adherens junction assembly agent cell-cell junction 19041755    
205116 VASP   actin cable formation agent cell-cell junction active 16613855  10660044    
206116 LPP   modification input 18413140    
206124 PIP5K1C   subnet input active   
206090 Vinculin   regulation of cell-cell adhesion agent cell-cell junction 17664339    
206169 SEC6  SEC8   establishment of epithelial cell apical/basal polarity agent cell-cell junction 14709721  17635938    
206094 Mena   modification input 16371509    
206088 Myosin VI   translocation input 17664339    
206102 Nezha   translocation input 19041755    
206109 DIAPH1   modification input inactive 19158278    
206175 MGAT3   modification input 18690644  16537539    
206168 exocyst   translocation input 17761530    
206112 Vinculin   translocation input 9566974  10660044    
206167 SEC6  SEC8   translocation input cytoplasm 14709721  17635938    
206171 Syntaxin-4   translocation input 17635938    
206093 ROCK1   modification input 16030252    
206172 Ephrin A1  EPHA2   modification input integral to membrane 10511313  10769210  19193766    
206165 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   Wnt receptor signaling pathway inhibitor cell-cell junction 11381089  10085258    
206085 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin  EPLIN   modification input cell-cell junction 18093941    
206106 DIAPH1   modification input inactive 17940061    
206100 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   cortical microtubule organization agent cell-cell junction 11056534  19041755  17635938    
206086 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin  EPLIN  cortical actin cytoskeleton   cortical actin cytoskeleton stabilization agent cell-cell junction 18093941    
206107 DIAPH1   adherens junction assembly agent cell-cell junction active 17940061