Related Signaling interaction pathway:

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VEGFR1 specific signals

Related component ;click for the further info from NCBI
eNOSHsp90Ca2+CaMAKT1
PKA C-alphaL-arginineNADPHO2L-citrulline
NONADPVEGFR1 homodimerVEGFA homodimerDAG
PDK1PI-3-4-5-P3PLGF homodimerNRP2VEGFA121
VEGFR121PI3KGAB1PLCgamma1PI-4-5-P2
PI-3KERK1-2-activeNRP1PKC alphaSck (SHC2)
IP3SHP2PKC beta2HIF1AVEGFR1
CBLCD2APNCK1VEGFB homodimerRasGAP
Caveolin-1ERK1-2VEGFR 121

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
206001 eNOS  Hsp90   translocation input plasma membrane 10908731  10376602  12171920  11978735  10376603  16839566    
202524 L-arginine   modification input cytoplasm 10908731  10376602  11978735  12171920  17466390  15162796  10376603    
206016 VEGFR1 homodimer   modification input plasma membrane 8621427    
205999 Ca2+   modification input cytoplasm   
200957 PDK1   translocation input cytoplasm 9637919    
206015 VEGFR1 homodimer   modification input plasma membrane 12796773    
206010 VEGFR1 homodimer  NRP2   modification input plasma membrane 11986311    
205991 AKT1   modification input cytoplasm active 16787925    
205992 PLCgamma1   modification input cytoplasm 9299537    
200607 PI-4-5-P2   modification input plasma membrane 11438544    
206004 ERK1-2-active   platelet activating factor biosynthetic process agent active 12598525  11704645    
206007 NRP1   modification input 11278319  10842181    
205997 PKC alpha   endothelial cell proliferation agent active 12598525  11704645    
205987 PI-3K   modification input cytoplasm 9600074  14633857    
206011 VEGFR1 homodimer  VEGFA homodimer   modification input plasma membrane active 9790910  16633338  12214271  10749680    
200251 Ca2+   translocation input calcium store 3919143  15879121  17675482  9820480  19158393  9722546  12598525  17242406  9398617  12482967  9115251  9435453  8125934    
206006 AKT1   endothelial cell proliferation agent cytoplasm active 9804796    
205986 SHP2   modification input cytoplasm 9722576  9600074    
205998 PKC beta2   endothelial cell proliferation agent active 12598525  11704645    
206017 HIF1A   transcription agent nucleus 9295307    
205993 PI-4-5-P2   modification input plasma membrane 12598525  11312102  9398617    
206013 VEGFR1 homodimer  VEGFA homodimer  CBL  CD2AP   ubiquitin-dependent protein catabolic process agent plasma membrane active 12649282  15001553    
205996 PKC beta2   modification input 12598525  11704645    
206009 NRP2   modification input 11986311    
205985 NCK1   modification input cytoplasm 9722576  9600074    
205995 PKC alpha   modification input 12598525  11704645  9398617    
206014 VEGFR1 homodimer   modification input plasma membrane 9751730    
206005 RasGAP   modification input cytoplasm 7824266    
206000 eNOS  Caveolin-1   modification input plasma membrane 11425855    
206003 ERK1-2   modification input 12598525  11704645    
206012 VEGFR1 homodimer  VEGFA homodimer   modification input plasma membrane active 12649282  15001553    
205989 PI3K  GAB1   translocation input cytoplasm active 16787925    
206008 VEGFR1 homodimer  NRP1   modification input plasma membrane 11986311