Related Signaling interaction pathway:

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Hedgehog signaling events mediated by Gli proteins

Related component ;click for the further info from NCBI
GLI2PolarisGLI2AGLI3Su(fu)
SIN3HDAC complexSPOPGLI1GLI3R
SMOPKA C-alphaPKC deltahFubeta Arrestin2
GLI3ACbpCBPPIAS1beta TrCP1
SCFMIMExportin 1AKT1SCF ubiquitin ligase complex
GLI2RCK1 familyIFT172Rab23Gi family
GTPGLI familyGLI family-activeKif3aGsk3beta
MEK1SHH NpCholesterolGNB1GNG2
GDPGalectin3PTCH1FOXA2

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
205814 GLI2   modification input cytoplasm 15930098  16254602    
205801 GLI3   modification input cytoplasm 11960000    
205827 GLI2  SPOP   catabolic process agent inactive 16740475    
205817 GLI1   embryonic limb morphogenesis agent nucleus active 10693759  10725236    
205792 GLI3   modification input cytoplasm inactive 10693759    
205808 GLI2   modification input cytoplasm 16424016    
205796 GLI2  Su(fu)   modification input cytoplasm inactive 10806483  16908539    
205821 GLI3   modification input cytoplasm 16061793    
205824 GLI3   modification input cytoplasm 16740475    
205798 GLI2A   translocation input cytoplasm active 10806483  16908539    
205822 GLI3A   modification input nucleus active 10075717    
205803 Su(fu)   modification input nucleus 14611647    
205794 GLI3   modification input cytoplasm inactive 16705181    
205830 MIM   modification input cytoplasm 15545630    
205799 Su(fu)   modification input nucleus 14611647  11960000    
205787 GLI1   translocation input nucleus active 10559945    
205831 MIM   modification input cytoplasm 15545630    
205791 GLI2   modification input cytoplasm 16537363    
205795 GLI1  Su(fu)   modification input cytoplasm inactive 10806483  16908539    
205790 GLI2   modification input cytoplasm inactive 16611981    
205788 GLI2   modification input cytoplasm 16611981    
205816 Polaris   embryonic digit morphogenesis agent 15930098    
205819 GLI2   modification input cytoplasm 14603322    
205786 GLI3   modification input cytoplasm 11449277  16364285    
205825 GLI3  SPOP   catabolic process agent inactive 16740475    
205805 GLI1   modification input nucleus 16885213    
205828 GLI family   modification input nucleus 16908539    
205835 GLI3   modification input cytoplasm 16061793    
205783 GLI2   modification input cytoplasm 10564661  10531011    
205782 GLI1   modification input cytoplasm 10564661  10531011  16459297    
205812 GLI2A   transcription agent nucleus active 15930098  11748151  16424016  9636069    
205789 GLI2   modification input cytoplasm inactive 16611981    
205809 MEK1   modification input 16424016    
205813 GLI3   modification input cytoplasm 15930098  16254602    
205823 GLI3A  CBP   transcription agent nucleus active 10075717    
205826 GLI2   modification input cytoplasm 16740475    
205804 Gi family  GNB1  GNG2  GDP   modification input inactive 16885213    
205820 GLI2   modification input cytoplasm 14603322    
205802 Su(fu)   modification input cytoplasm 14611647    
205811 GLI2A   transcription agent nucleus active 15930098  11748151  16424016  15087129  9636069    
205800 GLI1   modification input nucleus 14611647  16254602  11960000    
205818 GLI1   forebrain development agent nucleus active 10725236    
205829 GLI family-active   neural tube patterning agent nucleus active 11748151  14723851  12812795  15215207    
205832 MIM  GLI2A   transcription agent nucleus active 15545630    
205806 GLI1   transcription agent nucleus active 16254602  15087129  16885213    
205833 MIM  GLI1   transcription agent nucleus active 15545630    
205810 GLI2   modification input cytoplasm 16424016    
205793 GLI3   modification input cytoplasm inactive 16705181    
205834 GLI3   modification input cytoplasm 16061793    
205807 PKC delta   modification input 16424016    
205797 GLI1   translocation input cytoplasm active 10806483  16908539    
205785 GLI2   modification input cytoplasm 11449277  16908539  16364285    
205784 GLI3   modification input cytoplasm 10564661  10531011