Related Signaling interaction pathway:

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Nephrin/Neph1 signaling in the kidney podocyte

Related component ;click for the further info from NCBI
BADRac1GTPRAC1GDP
PI3K Class IA familyNephrinNEPH1beta Arrestin2Par3
Par6Atypical PKCsJNK familyMKK4Fyn
podocinNCK1-2N-WASPAKT1PI-3-4-5-P3
JUNGRB2CD2APCholesterolPLCgamma1
ZO-1PI-4-5-P2IP3DAGTRPC6
Ca2+

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
204556 BAD   apoptosis inhibitor inactive 19121340  9346240  12832477  15339792    
200503 Rac1  GTP   lamellipodium assembly agent active 12973357  12589802  11886862  12393875  18033240  15793570  15351743    
205340 RAC1  GDP   modification input inactive 18033240    
205368 Nephrin  NEPH1  beta Arrestin2   regulation of endocytosis agent integral to membrane 16968782    
205351 Nephrin  NEPH1  Par3  Par6  Atypical PKCs   positive regulation of NF-kappaB transcription factor activity inhibitor cell-cell junction 19497968    
205363 JNK family   modification input 11562357    
205324 Fyn   modification input 15200416  12668668  16543952  17923684    
205330 Nephrin  NEPH1  podocin  NCK1-2  N-WASP   cytoskeleton organization agent membrane raft 16525419  18212058  16543952    
205335 AKT1   modification input cytoplasm 18046313  18033240  15339792    
205365 JUN   modification input 11562357    
205359 Nephrin  NEPH1  podocin   modification input membrane raft 17923684    
205322 Nephrin  NEPH1   modification input integral to membrane 12424224  18715943  14633607  12660326  12646566    
205323 Nephrin  NEPH1   modification input integral to membrane 12424224  18715943  17923684  12660326  12646566  11562357    
205349 Nephrin  NEPH1   modification input cell-cell junction 19142224  18562307  19497968    
205332 Nephrin  NEPH1  podocin   modification input membrane raft 10514378  12832477  11733557    
205333 PI3K Class IA family   modification input 18274541  12832477    
205328 Nephrin  NEPH1  podocin   modification input membrane raft 16525419  18212058  16543952    
205356 Nephrin  NEPH1  podocin   modification input membrane raft 17079490    
205367 Nephrin  NEPH1   modification input integral to membrane 16968782    
205336 BAD   modification input 18046313  9346240  18385666  12832477    
205329 Nephrin  NEPH1  podocin  NCK1-2   modification input membrane raft 18212058    
205345 Nephrin  NEPH1  podocin   modification input membrane raft 19179337    
205327 Nephrin  NEPH1   modification input cell-cell junction 12578837    
205346 PI-4-5-P2   modification input plasma membrane 19179337    
205364 JNK family   translocation input cytoplasm active 11562357    
205360 Nephrin  NEPH1  podocin  GRB2   cytoskeleton organization agent membrane raft 17923684    
205357 TRPC6   modification input 17079490    
204577 Ca2+   modification input calcium store 8940018  19179337    
204552 PI-4-5-P2   modification input plasma membrane 12750173  10648629  18033240  11136732  11546794  9593664    
205331 PI3K Class IA family   modification input 18033240  12832477    
205350 Nephrin  NEPH1  Par3  Par6  Atypical PKCs   establishment of cell polarity agent cell-cell junction 19142224  18562307    
205326 Nephrin  NEPH1   modification input cell-cell junction 14570703  15579503  10742096  11562357  11733557  11549599    
205362 MKK4   modification input 11562357    
205325 Nephrin  NEPH1  podocin   modification input membrane raft 18212058  15579503  12668668  16543952  12846735  10504499