Related Signaling interaction pathway:

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IL23-mediated signaling events

Related component ;click for the further info from NCBI
IL23IL23RJAK2TYK2IFN-gamma
IL1 betaNF kappa B1 p50RelAI kappa B alphaIL23A
STAT1STAT1 (dimer)CD4PI-3KPI3K
CXCL9STAT3 (dimer )IL17F12R-LOXCD3E
IL6IL24IL12Rbeta1NOS2CCL2
STAT4STAT3STAT4 (dimer)IL12BIL18
IL18RIL2IL17SOCS3alpha3 Integrin
CXCL1STAT5ASTAT5A (dimer)IL19Myeloperoxidase
TNF-alpha

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
205291 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 11114383    
205318 IL23  IL23R  JAK2  TYK2   positive regulation of T cell mediated cytotoxicity agent integral to membrane active 15308705    
205309 IL23  IL23R  JAK2  TYK2   keratinocyte proliferation agent integral to membrane active 17074928    
205319 IL1 beta   transcription agent 15583831  16622035    
205284 STAT1   modification input 12023369    
205317 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205306 IL23   positive regulation of dendritic cell antigen processing and presentation agent extracellular region 12023338    
205292 PI-3K   modification input plasma membrane 16622035    
205315 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205289 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 15657292  16200070    
205293 STAT3 (dimer )   transcription agent active 12417590  15657292    
205314 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205316 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205294 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 15657292    
205308 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 17074928    
205281 IL23   modification input extracellular region 11114383  12023369  9038232    
205312 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205310 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770  16919486  17030949    
205301 IL23  IL23R  JAK2  TYK2   T cell proliferation agent integral to membrane active 11114383    
205283 STAT4   modification input cytoplasm 11114383  12023369    
205299 NF kappa B1 p50  RelA  I kappa B alpha   modification input cytoplasm 16622035    
205286 STAT4   modification input cytoplasm 12023369    
205321 IL23A   modification input   
205300 NF kappa B1 p50  RelA  I kappa B alpha   pathway input cytoplasm active1   
205290 IL18  IL18R   transcription agent active 12023369    
205296 IL23R   modification input integral to membrane 12023369    
205288 STAT3 (dimer )   transcription agent active 12417590  16622035  15657292  16200070  16200068    
205304 IL23  IL23R  JAK2  TYK2   positive regulation of chronic inflammatory response agent integral to membrane active 16648837  16670770  16919486  12610626  17030949    
205287 IL23  IL23R  JAK2  TYK2   modification input integral to membrane active 16698929    
205295 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 15657292    
205311 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 17030949    
205305 IL23  IL23R  JAK2  TYK2   positive regulation of humoral immune response agent integral to membrane active 14978083    
205285 STAT5A   modification input 12023369    
205303 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 12610626    
205307 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 17074928    
205313 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 16670770    
205302 IL23  IL23R  JAK2  TYK2   transcription agent integral to membrane active 15657292  12610626    
205282 STAT3   modification input 16622035  12023369    
205320 TNF-alpha   transcription agent extracellular region 15583831