Related Signaling interaction pathway:

Data buffering takes about 1 or more minute acording to the network size.



Paxillin-dependent events mediated by a4b1

Related component ;click for the further info from NCBI
alpha4beta1 IntegrinPaxillinVCAM1alphaL
beta2 IntegrinRAC1GDPPI-3KCRKL
CBLGIT1p130CasCrkDock1
ARF6GTPRac1TalinActin Cytoskeleton
PKAbeta7 Integrinactin cytoskeleton

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
204780 alpha4  beta1 Integrin  Paxillin  VCAM1   cell adhesion input 12794117    
204787 RAC1  GDP   modification input inactive 12589802  16227616  15793570    
204785 alpha4  beta1 Integrin  Paxillin   modification input 15793570    
200503 Rac1  GTP   lamellipodium assembly agent active 12973357  12589802  11886862  12393875  18033240  15793570  15351743    
204784 alpha4  beta1 Integrin  Paxillin  Talin  Actin Cytoskeleton   cell adhesion agent 16365170    
204781 alpha4  beta1 Integrin  Paxillin   modification input 12837751  11533025  15793570    
204782 alpha4  beta1 Integrin  Paxillin   modification input 16365170    
204777 alpha4  beta1 Integrin   modification input 10781578  10604475    
204786 ARF6  GDP   modification input plasma membrane inactive 15793570    
204778 alpha4  beta7 Integrin   modification input 10781578    
204779 alpha4  beta7 Integrin  Paxillin   modification input 16670268  7689608  7507598    
204783 alpha4  beta1 Integrin  Paxillin  Talin   modification input 16365170