Related Signaling interaction pathway:

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E-cadherin signaling in the nascent adherens junction

Related component ;click for the further info from NCBI
E-cadherinbeta cateninalpha cateninbeta7alphaE Integrin
PI-3KSrcKLEIPRac1GTP
Ca2+p120 cateninWAVE2ABI1Sra1
Nap1gamma cateninAP1M1PIP5K1CRAP1
GDPC3GRAC1IQGAP1CDC42
VAV2Arp23 complexCRKCyclin D1
ZO-1ARF6NME1Tiam1Mena
AKT1PI-3-4-5-P3PI-4-5-P2I-afadinE-cadherin(dimer)
CortactinDLG1RhoACK2

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
204243 E-cadherin  beta catenin  alpha catenin   modification input basolateral plasma membrane 7969453    
204211 PI-3K   translocation input 16170364  15556934    
204234 KLEIP   modification input cytoplasm 14668487    
204203 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   regulation of calcium-dependent cell-cell adhesion agent cell-cell junction 14610055  12427869  18632982    
204222 WAVE2   modification input cytoplasm 19158278  17164293    
204201 E-cadherin  beta catenin  alpha catenin   modification input cell-cell junction   
204238 E-cadherin  gamma catenin  alpha catenin   modification input basolateral plasma membrane 2349235    
204250 AP1M1   modification input 17261850  17620337    
202027 RAP1  GDP   modification input inactive 16170364  15254236  15504743  16472674    
204245 E-cadherin  beta catenin  alpha catenin  beta7  alphaE Integrin   regulation of heterotypic cell-cell adhesion agent basolateral plasma membrane 7969453    
204235 KLEIP   actin cytoskeleton organization agent cell-cell junction 14668487    
204205 Src   modification input inactive 17553930  16170364  15556934    
204212 PI-3K   modification input cell-cell junction 17553930  16170364  11744701  11716761  15254236  10383446    
204246 E-cadherin  gamma catenin  alpha catenin  beta7  alphaE Integrin   regulation of heterotypic cell-cell adhesion agent basolateral plasma membrane 7969453    
204197 E-cadherin  beta catenin   translocation input basolateral plasma membrane 10402472  15263019    
204213 VAV2   modification input inactive 16170364    
204220 CDC42  GTP   regulation of cell-cell adhesion agent cell-cell junction active 15254236    
204229 Arp2  3 complex   regulation of actin nucleation agent cell-cell junction active 15159390  15024035  17164293  11882288    
204207 C3G   modification input inactive 16170364  15254236    
204233 Cyclin D1   positive regulation of S phase of mitotic cell cycle agent nucleus 18187454    
204217 CDC42  GTP   modification input cell-cell junction active 10473551  9694656    
204230 ZO-1   translocation input 9214391    
204232 Rac1  GTP   transcription agent cell-cell junction active 18187454    
204214 RAC1  GDP   modification input inactive 16170364  11744701  11329369  12447393  11457821    
204224 ABI1  Sra1  Nap1   subnet input cell-cell junction   
204225 Mena   translocation input 16371509    
204206 CRK   modification input inactive 16170364    
204200 E-cadherin  beta catenin  alpha catenin   modification input basolateral plasma membrane 12770907  10202138  6976838  19114658  14585958    
204249 AKT1   translocation input plasma membrane active 10383446    
204248 AKT1   modification input 11027222  10383446  11312610  11546794    
204247 PI-4-5-P2   modification input plasma membrane 10383446    
204202 E-cadherin  Ca2+  beta catenin  alpha catenin   modification input cell-cell junction 15857834  10629228  12427869    
204198 E-cadherin  beta catenin   translocation input recycling endosome 17261850  10402472    
204226 Arp2  3 complex   modification input cell-cell junction inactive 15024035    
204204 E-cadherin  beta catenin  alpha catenin  p120 catenin   modification input cell-cell junction 10202138  12370292  10201395    
204237 E-cadherin  gamma catenin   modification input basolateral plasma membrane 8207061  2788574  2349235    
204231 ZO-1   adherens junction assembly agent cell-cell junction 9214391    
204239 E-cadherin  Ca2+  beta catenin  alpha catenin  p120 catenin   subnet input cell-cell junction   
204221 Nap1   modification input 19158278  17164293    
204244 E-cadherin  gamma catenin  alpha catenin   modification input basolateral plasma membrane 7969453    
204219 CDC42  GDP   modification input cell-cell junction inactive 15254236    
204228 Arp2  3 complex   modification input cell-cell junction inactive 15159390  15024035    
204209 PI-3K   translocation input 14699157    
204227 Cortactin   translocation input cytoplasm 15024035    
204196 E-cadherin  beta catenin   modification input basolateral plasma membrane 8207061  10037790  7954478  2788574  2349235    
204236 E-cadherin  beta catenin  alpha catenin   modification input cell-cell junction 10980705    
204223 Arp2  3 complex   modification input cell-cell junction inactive 16371509  10660044    
204215 Rac1  GTP   modification input cell-cell junction active 11329369  10473551  9694656    
204242 E-cadherin  beta catenin   modification input basolateral plasma membrane 12432063    
204208 DLG1   modification input cell-cell junction 9512503  14699157