Related Signaling interaction pathway:

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Direct p53 effectors

Related component ;click for the further info from NCBI
p53 (tetramer)METPro-Caspase 10DroshaDGCR8
p68 helicasePIRH2NF-YTIGARBAX
FASTRAILR2BCL6CSE1LP53R2
PTENDDB2HIC1p53Cbp
p300CARM1PRMT1 (tetramer)GCN5-LADA2B
TAF9GADD45AAPAF-1MMP2BAK
Cyclin G1RB1JUNMSH2ATF3
PA26GPX1AMIDBTG2SP1
E2F1-3DPCaveolin-1PTGFBEGFR
Pro-Caspase 6S100A2PLK3TRAILR3MKP1
IPAFE2LIFp53CSVTGFA
E2FBP1Cyclin KPRMT1DeltaNp63 alphap63
BRG1POU4F1HZFHDAC2p21CIP1
P73KAI1Pro-Caspase 1PMLPRKAB1
RGC32TSC2VDRp53RFPASPP
PCNAAPCTRAILR4BNIP3LCSPG2
MCL1BK2CBFHSP70-1ASLUG
PUMAREDD1TRRAPMDM2FDXR
COP1p53DINP1TYRP1Cyclin B1PIDD
BCLGDKK1fractalkineHGFRPS27L
ET2Cathepsin DOsteopontinPMS2NOXA
PPM1JNDRG1maspinCOL18A1BCL2 subfamily
IGFBP3MAP4K4TSAP6HTTFOXA1
AFPEPHA2IRF5JMYSAP
ASCMCG10DUSP5POU4F2PAI
SCN3BBCL2BIDPERPTRAILR1
14-3-3 SPIG3MIR34ABLIMP1TAP1
MLH1

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203994 p53 (tetramer)   transcription agent nucleus 9920903    
203973 p53 (tetramer)   transcription agent nucleus 14688482    
204013 p53 (tetramer)  Drosha  DGCR8  p68 helicase   primary microRNA processing agent nucleus 19626115    
204014 p53 (tetramer)   transcription agent nucleus 12654245    
203899 p53 (tetramer)  NF-Y   G2/M transition DNA damage checkpoint agent nucleus 15831478    
203933 p53 (tetramer)   transcription agent nucleus 16140933    
203951 BAX   activation of caspase activity by cytochrome c agent active 16151013  14963330  12667443    
203920 p53 (tetramer)   transcription agent nucleus 9841917    
203945 p53 (tetramer)   transcription agent nucleus 15289308  10777207    
203965 p53 (tetramer)   transcription agent nucleus 16249378    
203929 p53 (tetramer)   transcription agent nucleus 17719542  10716435    
203936 p53 (tetramer)   transcription agent nucleus 17409411  11545734    
203921 p53 (tetramer)   transcription agent nucleus 11971958    
203988 p53 (tetramer)   transcription agent nucleus 16301995    
203907 p53  Cbp  p300  CARM1  PRMT1 (tetramer)   transcription agent nucleus 18250150  15186775    
203935 p53 (tetramer)   transcription agent nucleus 11559530    
203995 p53 (tetramer)   transcription agent nucleus 9343394    
203953 BAK  p53   activation of caspase activity by cytochrome c agent mitochondrion 15077116    
203910 p53 (tetramer)   transcription agent nucleus 17110336    
203939 p53 (tetramer)   transcription agent nucleus 8119988    
203904 p53 (tetramer)   transcription agent nucleus 10984493  11350971    
203961 p53 (tetramer)   transcription agent nucleus 12372430    
204006 p53 (tetramer)   transcription agent nucleus 9926927    
203932 p53 (tetramer)   transcription agent nucleus 16140933    
203950 BAX   modification input 14963330    
203914 p53 (tetramer)   transcription agent nucleus 15273740    
203969 p53 (tetramer)   transcription agent nucleus 11814693    
203974 p53 (tetramer)   transcription agent nucleus 10684646    
203986 p53 (tetramer)   transcription agent nucleus 10618379    
203984 p53 (tetramer)   transcription agent nucleus 8887630    
203972 p53 (tetramer)   transcription agent nucleus 12089322    
204004 p53 (tetramer)   transcription agent nucleus 10094469    
203931 p53 (tetramer)   transcription agent nucleus 16140933    
203947 p53 (tetramer)   transcription agent nucleus 16230375    
203979 p53 (tetramer)   transcription agent nucleus 12890671    
203997 p53 (tetramer)   transcription agent nucleus 15580302    
203919 p53 (tetramer)   transcription agent nucleus 18046411    
203956 p53 (tetramer)   transcription agent nucleus 15735003    
203954 p53 (tetramer)   transcription agent nucleus 7651386    
203960 p53 (tetramer)   transcription agent nucleus 12692263    
203975 p53 (tetramer)   transcription agent nucleus 11988847    
203906 p53 (tetramer)   modification input nucleus 15186775    
203942 p53 (tetramer)   transcription agent nucleus 14576823    
203916 p53 (tetramer)   transcription agent nucleus 7796420  17719541  19011621  18250150  17409421  17938176  17707234    
203943 p53 (tetramer)   transcription agent nucleus 11314010    
203976 p53 (tetramer)   transcription agent nucleus 9736732    
203971 p53 (tetramer)   transcription agent nucleus 11278253    
204000 p53 (tetramer)   transcription agent nucleus 14992722    
203934 p53 (tetramer)   transcription agent nucleus 16140933  17409411    
203970 p53 (tetramer)   transcription agent nucleus 17146433    
203937 p53 (tetramer)   transcription agent nucleus 17409411    
203959 p53 (tetramer)   transcription agent nucleus 16651407    
203990 p53 (tetramer)   transcription agent nucleus 12853982    
203911 p53 (tetramer)   transcription agent nucleus 11850816  15598651  11684014  11278953  17189187    
203928 p53 (tetramer)   transcription agent nucleus 8570655    
203925 p53 (tetramer)   transcription agent nucleus 11279192    
203946 p53 (tetramer)   transcription agent nucleus 16230375    
203968 p53 (tetramer)   transcription agent nucleus 15607964    
203958 p53 (tetramer)   transcription agent nucleus 12438652    
203952 p53   modification input mitochondrion 15077116    
203924 p53 (tetramer)   modification input nucleus 11279192    
203967 p53 (tetramer)   transcription agent nucleus 10748162    
203897 CBF   transcription agent 8418500    
203917 p53 (tetramer)   transcription agent nucleus 17719541  11463392  19011621  18250150  15790310  17707234    
203922 p53 (tetramer)   transcription agent nucleus 12453409    
203918 p53 (tetramer)   transcription agent nucleus 7651818  8319905  17409421  12138177    
203927 p53 (tetramer)   transcription agent nucleus 12370809  17409421    
204003 p53 (tetramer)   transcription agent nucleus 15103385    
203908 p53 (tetramer)   transcription agent nucleus 16286009  11463392  18250150  15790310  17707234  17189187  17189186    
203941 p53 (tetramer)   transcription agent nucleus 11511362    
203957 p53 (tetramer)   transcription agent nucleus 10640990    
203901 SP1   transcription agent nucleus 15710382    
203993 p53 (tetramer)   transcription agent nucleus 10973264    
203962 p53 (tetramer)   transcription agent nucleus 15958553    
203940 p53 (tetramer)   transcription agent nucleus 11032029    
203926 p53 (tetramer)   transcription agent nucleus 11840333  10777218  17409421    
203978 p53 (tetramer)   transcription agent nucleus 10919640    
203912 p53 (tetramer)   transcription agent nucleus 18485870  7796420  17719541  18250150  17409421  17938176  17707234    
203898 NF-Y   modification input nucleus 15831478    
203987 p53 (tetramer)   transcription agent nucleus 9023107    
203983 p53 (tetramer)   transcription agent nucleus 16260627    
203981 p53 (tetramer)   transcription agent nucleus 16260627    
203977 p53 (tetramer)   transcription agent nucleus 9619826    
204010 p53 (tetramer)   transcription agent nucleus 11807984    
203902 p53 (tetramer)   transcription agent nucleus 15781865    
204016 p53 (tetramer)   transcription agent nucleus 15598651    
203982 p53 (tetramer)   transcription agent nucleus 16260627    
203996 p53 (tetramer)   transcription agent nucleus 15377670    
203955 p53 (tetramer)   transcription agent nucleus 10692390    
203909 p53 (tetramer)   transcription agent nucleus 17110336  7796420  17719541  18250150  17409421  17938176  17707234    
203963 p53 (tetramer)   transcription agent nucleus 15958553    
203949 p53  BCL2 subfamily   modification input mitochondrion 16151013    
203991 p53 (tetramer)   transcription agent nucleus 7566179    
204018 p53 (tetramer)   transcription agent nucleus 16286009    
203948 p53   modification input mitochondrion 17268548  12667443    
203964 p53 (tetramer)   transcription agent nucleus 15958553    
204009 p53 (tetramer)   transcription agent nucleus 12606722    
203900 p53 (tetramer)   modification input nucleus 15710382    
203930 p53 (tetramer)   transcription agent nucleus 16278683    
203895 FOXA1   transcription agent nucleus 9891062    
203985 p53 (tetramer)   transcription agent nucleus 11641774    
203992 p53 (tetramer)   transcription agent nucleus 11973653    
204015 p53 (tetramer)   transcription agent nucleus 10518217  11850816  15598651  11278953  17189187    
204007 p53 (tetramer)   transcription agent nucleus 15378026    
204002 p53 (tetramer)   transcription agent nucleus 14730312    
203998 p53 (tetramer)   transcription agent nucleus 10891498    
203980 p53 (tetramer)   transcription agent nucleus 12944906    
204012 p53 (tetramer)   modification input nucleus 19626115    
204017 p53 (tetramer)   transcription agent nucleus 11850816  15598651  17145718  11278953  17189187    
203938 p53 (tetramer)   transcription agent nucleus 7479001    
204005 p53 (tetramer)   transcription agent nucleus 15334053    
203896 POU4F1   transcription agent nucleus 10329733    
203966 p53 (tetramer)   transcription agent nucleus 12402042    
203999 p53 (tetramer)   transcription agent nucleus 14707288    
203944 p53 (tetramer)   transcription agent nucleus 15289308    
203923 p53 (tetramer)   transcription agent nucleus 9659898  17719541    
203913 p53 (tetramer)   transcription agent nucleus 18485870  17719542  11919562  11684014    
204011 p53 (tetramer)   transcription agent nucleus 17554199    
204001 p53 (tetramer)   transcription agent nucleus 17264218    
204008 p53 (tetramer)   transcription agent nucleus 10618714  12857899    
203903 p53 (tetramer)   transcription agent nucleus 15781865