Related Signaling interaction pathway:

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IL2 signaling events mediated by PI3K

Related component ;click for the further info from NCBI
ASMIL2IL2R alphabetagamma
JAK1LCKJAK3SHCGRB2
SOS1GAB2SHP2PI3Kglucosylceramide
BCL-XNF kappa B1 p50RelAAKT1Rac1
GTPGCSMYCFOXO3APKC zeta
ceramideUDP-D-glucoseBCL2PI-4-5-P2PI-3-4-5-P3
PhosphatidylcholineSMSsphingomyelinDAGMyb
IL2R betamTORp70S6KcAMPNFAT1-c-4
CaMCa2+Calcineurin A alpha-beta B1RAC1GDP
PI-3K40S S6 ribosomal protein 40s Ribosomal subuniteIF3E2F1
Hsp90TERT

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203815 ASM   modification input 15271800    
203821 glucosylceramide   cell proliferation agent 15271800    
203806 BCL-X   cell survival agent mitochondria 9092570    
200541 NF kappa B1 p50  RelA   pathway input nucleus active   
203814 AKT1   modification input cytoplasm 12393431    
203816 GCS   modification input 15271800    
203811 AKT1   transcription agent plasma membrane active 9108028    
203825 FOXO3A   modification input nucleus 11994454    
203832 PKC zeta   T cell proliferation agent active 7737351    
203818 ceramide   modification input 15271800    
203828 BCL2   cell survival agent mitochondria   
203803 PI-4-5-P2   modification input plasma membrane 1652056  9029085    
203819 ceramide   modification input 15271800    
203824 Myb   cell survival agent 11486019    
203805 IL2  IL2R beta  gamma  JAK1  LCK  JAK3  PI3K   transcription agent integral to membrane active 9092570    
203812 mTOR   transcription agent active 9108028  7736574    
203802 PKC zeta   actin cytoskeleton organization agent active 9029085  7589144    
203804 AKT1   modification input cytoplasm 9162082  8617294  10982827  9108028  12525482    
203808 p70S6K   modification input 9162082  7760801  1614535  7528328    
203830 NFAT1-c-4   modification input nucleus inactive 7543780    
203813 RAC1  GDP   modification input inactive 12393431    
203817 SMS   modification input 15271800    
203157 mTOR   modification input 15051500  10567225  1614535  16027121    
203820 sphingomyelin   cell proliferation agent 15271800    
203809 40S S6 ribosomal protein   40s Ribosomal subunit  eIF3   modification input 10373522    
203831 NFAT1-c-4   transcription agent nucleus active 9771966    
203810 E2F1   modification input nucleus inactive 10373522    
203829 CaM  Ca2+  Calcineurin A alpha-beta B1   modification input 9771966  7543780    
203823 E2F1   transcription agent nucleus active 3523754  11486019    
203827 MYC   cell proliferation agent nucleus   
203801 PKC zeta   modification input 7737351  9029085    
203826 FOXO3A   cell survival agent nucleus inactive 11994454    
203833 NF kappa B1 p50  RelA   translocation input cytoplasm active 7543780    
203822 AKT1   modification input plasma membrane active 15843522