Related Signaling interaction pathway:

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EGFR-dependent Endothelin signaling events

Related component ;click for the further info from NCBI
EGFEGFR dimerSHCGRB2SOS1
HRASGDPGTPmTOREGFR
ETA receptorEndothelin-1Ca2+

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203662 EGF  EGFR dimer  SHC   modification input integral to membrane active 8596637  10499523    
203663 HRAS  GDP   modification input inactive 8596637  10499523    
203664 mTOR   modification input 10499523    
203660 EGF  EGFR   modification input integral to membrane 8596637  16261333  10499523  16391241    
203661 EGF  EGFR dimer   modification input integral to membrane active 8596637  10499523    
203665 mTOR   pathway input active 15051500    
203659 EGF   modification input extracellular region 8596637  9595433  16261333  10499523  16391241