Related Signaling interaction pathway:

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PLK1 signaling events

Related component ;click for the further info from NCBI
PLK1PRC1-2MKLP2APCC
HCDH1KizunaKIF2ACenexin 1WEE1
beta TrCP1-2PP2A-alpha B56Bub1Hec1SPC24
PBIP1sSgo1CENPEEMI1Cyclin B1
CDK1TCTPAurora ABORAhSgo1
ROCK2RhoAGTPNudCGRASP65
GM130RAB1CLASPINCDC20BUBR1
PPP1CBMYPT1NLPgamma TubulinECT2
CDC25BCDC25CPAK1CohesinSA2
CDC14BPICHINCENPTPX2MAD2

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203547 PLK1   modification input active 7790358  12939256  17351640  14734534    
203550 PLK1   proteasomal ubiquitin-dependent protein catabolic process input active 9734353  14734534    
203517 Kizuna   spindle stabilization agent pericentriolar material 16980960    
203557 KIF2A   modification input microtubule 19351716    
203548 PLK1  PRC1-2   cytokinesis agent spindle midzone 17351640    
203521 PLK1   translocation input active 16966375    
203496 WEE1   proteasomal ubiquitin-dependent protein catabolic process input 15350223  15070733    
203560 PP2A-alpha B56   translocation input 16580887    
203516 Kizuna   modification input pericentriolar material 16980960    
203541 Hec1  SPC24   translocation input 15964272    
203538 PLK1  PBIP1   chromosome segregation agent kinetochore 17081991    
203522 sSgo1   modification input 18331714    
203542 CENPE   translocation input 15964272    
203556 PLK1   spindle assembly agent centrosome active 18427546    
203558 KIF2A   positive regulation of microtubule depolymerization agent spindle 19351716    
203505 EMI1   modification input 15148369  15469984    
203513 TCTP   microtubule cytoskeleton organization agent 12167714    
203539 PLK1  PBIP1   modification input kinetochore 17081991    
203494 PLK1   modification input 18566290  18615013    
203525 hSgo1   translocation input centrosome 16580887    
203552 ROCK2   modification input 17446864    
203533 NudC   modification input outer kinetochore of condensed chromosome 16860740  12852857    
203526 GRASP65  GM130  RAB1  GTP   modification input Golgi apparatus 15678101    
203546 MKLP2  PLK1   microtubule-based process agent microtubule 12939256    
203504 CLASPIN   proteasomal ubiquitin-dependent protein catabolic process input active 16934469  16885021  16885022    
203503 CLASPIN   modification input active 16934469  16885021  16885022    
203495 WEE1   modification input 15350223  15070733    
203489 PLK1   proteasomal ubiquitin-dependent protein catabolic process input active 18552834  9734353    
203532 BUBR1   regulation of attachment of spindle microtubules to kinetochore agent outer kinetochore of condensed chromosome 17785528    
203554 PLK1   modification input centrosome active 18477460    
203506 EMI1   proteasomal ubiquitin-dependent protein catabolic process input 15148369  15469984    
203551 PLK1   spindle elongation agent active 14734534    
203553 ROCK2   cytokinesis agent active 17446864    
203528 GRASP65  GM130  RAB1  GTP  PLK1   G2/M transition of mitotic cell cycle inhibitor Golgi apparatus 15678101    
203492 Aurora A   modification input active 18615013    
203514 NLP  gamma Tubulin   modification input centrosome 12852856    
203515 gamma Tubulin   spindle assembly agent centrosome 12852856    
203540 PBIP1   proteasomal ubiquitin-dependent protein catabolic process input kinetochore inactive 17081991    
203565 ECT2   translocation input 17488623  17360533    
203531 BUBR1   modification input outer kinetochore of condensed chromosome 17785528    
203498 Cyclin B1  CDK1   modification input inactive 15350223    
203545 MKLP2   modification input microtubule 12939256    
203527 GRASP65  GM130  RAB1  GTP   modification input Golgi apparatus 11050165    
203500 BORA   modification input 18521620  18378770    
203511 TCTP   modification input 12167714    
203509 CDC25C   translocation input cytoplasm 11897663    
203508 CDC25C   modification input cytoplasm 10980711  11897663    
203530 BUBR1   modification input outer kinetochore of condensed chromosome 17785528    
203519 Aurora A   subnet input spindle pole active   
203555 PLK1   modification input centrosome active 18427546    
203524 Cohesin  SA2   modification input chromosome 15737063    
203510 PLK1   regulation of mitotic centrosome separation agent active 8991084    
203518 Aurora A   translocation input active 16418575    
203487 APC  C  HCDH1   modification input 18662541    
203523 sSgo1   regulation of centriole-centriole cohesion inhibitor spindle pole 18331714    
203564 PICH   modification input chromosome 18418076  17218258    
203491 PLK1   modification input 18566290    
203488 PLK1   proteasomal ubiquitin-dependent protein catabolic process input 10980711  18662541    
203529 PLK1   Golgi organization agent active 11447294    
203563 PICH   modification input chromosome 18418076  17218258    
203486 CDC14B   translocation input nucleolus 18662541    
203497 Cyclin B1  CDK1   modification input active 8428596  15350223    
203534 PLK1   translocation input active 16860740    
203535 NudC   metaphase plate congression agent outer kinetochore of condensed chromosome 16860740    
203561 Bub1   modification input 16760428    
203520 TPX2   translocation input 16418575    
203501 BORA   proteasomal ubiquitin-dependent protein catabolic process input 18521620  18378770    
203562 PLK1   translocation input active 16760428    
203549 MKLP2  PLK1   cytokinesis agent microtubule 12939256    
203537 MAD2   translocation input 15964272  17081991    
203499 Cyclin B1  CDK1   G2/M transition of mitotic cell cycle agent active 15350223  10980711    
203536 PLK1   modification input active 17081991    
203493 PLK1   modification input 18615013    
203512 TCTP   modification input 12167714    
203543 APC  C  CDC20   translocation input 15964272