Related Signaling interaction pathway:

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EGF receptor (ErbB1) signaling pathway

Related component ;click for the further info from NCBI
EGFREGFFAKPI3K Class IA familyRAS family
GDPGTPGRB2SOS1p46 SHC
DAGSHP2GAB1PTP1BSHP1
GNAI1GNAI3RasGAPGelsolinSTAT3
JAK1-JAK2PIP5K1CTalinSrcERK1-2-active
p52 SHCSTAT1N-WASPp66 SHCPAK1
PI-4-5-P2PLCgamma1IP3Gab1NCK1-2

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203417 EGFR  EGFR  EGF  EGF  FAK   cell migration agent integral to membrane 9454735  10806474    
203416 EGFR  EGFR  EGF  EGF   modification input integral to membrane 10806474    
203420 PI3K Class IA family   subnet input plasma membrane active   
203369 RAS family  GDP   modification input inactive 8490966  7970708  8479541  8386805  8479536    
203372 EGFR  EGFR  EGF  EGF  p46 SHC   modification input integral to membrane 7518560  8479536  9049300  8479540    
203424 DAG   subnet input   
203387 SHP2   translocation input 11134009    
203378 EGFR  EGFR  EGF  EGF   modification input integral to membrane 12424235  9355745    
203379 SHP1   modification input 9733788  9038217  7673163    
203373 RAS family  GDP   modification input inactive 8479536  9049300  8479540    
203393 RAS family  GTP   modification input plasma membrane active 9121432  11134009  2005883  15574420    
203422 EGFR  EGFR  EGF  EGF   subnet input integral to membrane   
203418 Gelsolin   cell migration agent actin cytoskeleton active 11950594  12952932  7962064  8106552    
203384 PI3K Class IA family   modification input inactive 16055672  15550174  10913131    
203405 STAT3   modification input cytoplasm 9079708  15284024    
203427 EGFR  EGFR  EGF  EGF   modification input integral to membrane 8816994  6090944  1860884  10816576    
203392 RAS family  GTP   modification input plasma membrane active 9121432  11134009  2005883  15574420    
203430 PIP5K1C  Talin   cell migration agent 17635937    
203415 Src   subnet input active   
203388 EGFR  EGFR  EGF  EGF  GRB2  GAB1   modification input integral to membrane 12024020  15574420    
203426 STAT3   subnet input   
203390 EGFR  EGFR  EGF  EGF  GRB2  GAB1   modification input integral to membrane 11134009  15574420    
203408 EGFR  EGFR  EGF  EGF  GRB2  SOS1   modification input integral to membrane 7592690  7478553  7478566  8621459    
203389 EGFR  EGFR  EGF  EGF  GNAI1  GNAI3  GAB1   modification input integral to membrane 12024020  15574420    
203368 EGFR  EGFR  EGF  EGF  p52 SHC   modification input integral to membrane 8940013  8479540  1322798  7689150  7518560  7898933  7923364  8479536    
203403 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9079708  15284024    
203425 STAT1   subnet input   
203398 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9307968  8895577    
203410 EGFR  EGFR  EGF  EGF  p66 SHC   modification input integral to membrane 9346957    
203376 RAS family  GTP   modification input plasma membrane active 10669730  9121432  14560030  2005883    
203406 EGFR  EGFR  EGF  EGF  p52 SHC  GRB2  SOS1   modification input integral to membrane 7592690  7478553  7478566  8621459  8626525    
203428 PIP5K1C   modification input plasma membrane 17635937    
203395 EGFR  EGFR  EGF  EGF   modification input integral to membrane 12522133    
203391 EGFR  EGFR  EGF  EGF  GNAI1  GNAI3  GAB1   modification input integral to membrane 11134009  15574420    
203367 EGFR  EGFR  EGF  EGF   modification input integral to membrane 8034616  8628261  7518560  7527043  7681824  9049300  8479540    
203401 PI-4-5-P2   modification input plasma membrane 1700866    
203371 EGFR  EGFR  EGF  EGF   modification input integral to membrane 1623525  7518560  8479536  9346957  9049300    
203429 PIP5K1C   modification input plasma membrane 17635937    
203380 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9733788  9038217  7673163    
203382 EGFR  EGFR  EGF  EGF  GRB2   modification input integral to membrane 10648629  15550174  8596638  10913131    
203394 EGFR  EGFR  EGF  EGF   modification input integral to membrane 8798379  18269246  9989831  8824201    
203374 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9642214  14560030  10411909    
203419 RAS family  GTP   subnet input plasma membrane active   
203385 PI3K Class IA family   modification input inactive 19401591  15550174    
203386 SHP2   translocation input 11134009    
203404 STAT1   modification input cytoplasm 15284024    
203421 EGFR  EGFR  EGF  EGF   subnet input integral to membrane   
203423 IP3   subnet input   
203375 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9121432  1850098  14560030  2236073  1689011  2005883    
203370 RAS family  GDP   modification input inactive 8490966  1322798  7970708  8621459  9049300  8479540    
203399 EGFR  EGFR  EGF  EGF  GRB2  N-WASP   cortical actin cytoskeleton organization agent integral to membrane 9307968  8895577    
203383 EGFR  EGFR  EGF  EGF   modification input integral to membrane 19401591  10648629  15550174  8596638  10913131    
203407 EGFR  EGFR  EGF  EGF  p46 SHC  GRB2  SOS1   modification input integral to membrane 7592690  7478553  7478566  8621459    
203377 PTP1B   modification input 9355745  12424235    
203366 EGFR  EGFR  EGF  EGF   modification input integral to membrane 8479541  8940013  8479540  1322798  7518560  7527043  7923364  8479536    
203402 Gelsolin  PI-4-5-P2   modification input plasma membrane 11950594  8707848    
203400 EGFR  EGFR  EGF  EGF   modification input integral to membrane 2176151  1689310  2173144  1700866  1315766  2171993  7962064  2153914  7993895  1537335    
203413 Src   modification input 10075741  7542246  10675331  7488034  18156174  14963038  7525285  7823926  12464621    
203411 p66 SHC   modification input 9346957  9049300    
203381 EGFR  EGFR  EGF  EGF   modification input integral to membrane 14498832  10913131    
203409 EGFR  EGFR  EGF  EGF   modification input integral to membrane 9346957  9049300    
203414 Src   subnet input active