Related Signaling interaction pathway:

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mTOR signaling pathway

Related component ;click for the further info from NCBI
TSC1TSC2AKT1eIF4EeIF4G1
eIF4A1eIF4BRNAeIF340s Ribosomal subunit
60s Ribosomal Subunit80S RibosomeASK1PP5CmTOR
RapamycinRaptorRHEBGTPGBL
FKBP12p70S6KPP2API-3KIRS1
MNK1PDK1PDK2PIP3eEF2
Insulin ReceptorInsulinPI-4-5-P2PTENGDP
4E-BP1Amino AcidsLY294002AMPK40S S6 ribosomal protein
40S S6 ribosomal protein

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
203154 TSC1  TSC2   modification input active 12172553    
203172 eIF4E  eIF4G1  eIF4A1  eIF4B  RNA  eIF3  40s Ribosomal subunit   modification input   
203178 ASK1   modification input active 15328343  15218033    
203151 mTOR   modification input 15854902  15066126    
203161 p70S6K   modification input   
203168 eIF4E  eIF4G1  eIF4A1   modification input 1719376    
203175 ASK1   modification input cytoplasm 15218033    
203162 p70S6K   modification input active   
203173 80S Ribosome  RNA   translational elongation agent   
203149 PI-3K   modification input plasma membrane 11498541    
203166 eIF4E   modification input   
203152 PDK1   modification input plasma membrane   
203159 mTOR   modification input active   
203156 mTOR   modification input   
203167 eIF4E   modification input 6853548    
203180 eEF2   modification input active 8641294    
203150 PI-4-5-P2   modification input   
203155 RHEB  GTP   modification input active 15340059  12869586  12820960    
203157 mTOR   modification input 15051500  10567225  1614535  16027121    
203181 eEF2   peptide biosynthetic process agent inactive   
203174 4E-BP1   modification input inactive 10864916    
203148 Insulin Receptor  IRS1   modification input 11498541    
203158 mTOR   modification input active   
203153 AKT1   modification input   
203163 PP2A   modification input 11948686  10200280    
203169 eIF4B   modification input 15071500    
203165 eIF4E  4E-BP1   modification input   
203176 IRS1   modification input active 11287630    
203179 TSC2   modification input 14651849    
203160 p70S6K   modification input 12949840  12172553    
203170 40S S6 ribosomal protein   40s Ribosomal subunit  eIF3   modification input 15051500  15313464  6615839    
203177 ASK1   apoptosis agent active   
203164 4E-BP1   modification input   
203171 eIF4E  eIF4G1  eIF4A1  eIF4B  RNA   modification input 6853548