Related Signaling interaction pathway:

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IL1-mediated signaling events

Related component ;click for the further info from NCBI
IL1 beta fragmentIL1R1IL1RAPMYD88IRAK4
MYD88sIRAKTRAF6TAK1TAB1
TAB2UBC13UEV1APellinosMKK6
TICAM2IL1 alphaJNK1IL1RNIL1R2
TOLLIPJUNp62Atypical PKCsPI-3K
PI3KIRAKMMEKK3IKK complexELKS
NF kappa B1 p50RelAIL1 betaCaspase 1 (cleaved)

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
202892 IL1 beta fragment  IL1R1  IL1RAP  MYD88   modification input integral to membrane active 11960013  12538665    
202901 IRAK  TRAF6  TAK1  TAB1  TAB2   modification input integral to membrane active 11460167  12242293  10882101    
202912 MKK6   modification input 11460167  12242293  10882101    
202903 TRAF6  TAK1  TAB1  TAB2   modification input cytoplasm active 11460167    
202921 IRAK   modification input 12721283    
202889 IL1 alpha   modification input 7775431  2530587    
202914 JNK1   modification input 10882101    
202886 IL1RN   modification input 7878046    
202894 IL1 beta fragment  IL1R1  IL1RAP  MYD88  IRAK4  IRAK  TOLLIP   modification input integral to membrane active 8837778  12242293  11287640    
202170 JUN   modification input nucleus 9891069  10882101  12087092    
202896 IL1 alpha  IL1R1  IL1RAP  MYD88   modification input integral to membrane active 11960013    
202916 IRAK  TRAF6   modification input integral to membrane active 10747026    
202905 IRAK   proteasomal ubiquitin-dependent protein catabolic process input integral to membrane active 9261174    
202922 IL1 beta fragment  IL1R1  IL1RAP   modification input integral to membrane active 10373529  9360994    
202893 IL1 beta fragment  IL1R1  IL1RAP  MYD88  IRAK4   modification input integral to membrane active 12150927  9430229  11960013  10854325  12538665    
202919 IRAK  TRAF6   modification input integral to membrane active 17197697    
202920 IKK complex  ELKS   modification input cytoplasm 17197697    
202890 IL1 beta fragment   modification input active 7775431  1837145    
202909 IKK complex  ELKS   pathway input cytoplasm active   
202891 IL1 beta fragment  IL1R1  IL1RAP   modification input integral to membrane active 9430229  9374458    
202908 IKK complex  ELKS   modification input cytoplasm 11460167    
202902 IRAK  TRAF6  TAK1  TAB1  TAB2   modification input integral to membrane active 11460167  12242293  10882101    
202900 IRAK  TRAF6   modification input integral to membrane active 10882101  11287640    
202917 IKK complex  ELKS   modification input cytoplasm 10747026    
202923 NF kappa B1 p50   modification input 10373529  9360994    
202885 IL1 beta   modification input 7878046  8035875    
202898 IL1 alpha  IL1R1  IL1RAP  MYD88  IRAK4  IRAK  TOLLIP   modification input integral to membrane active 8837778  12242293    
202904 TRAF6  TAK1  TAB1  TAB2   modification input cytoplasm active 11460167    
202899 IRAK  TRAF6   modification input integral to membrane active 12242293  10882101    
202887 IL1 alpha   modification input 7878046    
202888 IL1RN   modification input 9062194    
202897 IL1 alpha  IL1R1  IL1RAP  MYD88  IRAK4   modification input integral to membrane active 11960013  10854325  12538665    
202895 IL1 alpha  IL1R1  IL1RAP   modification input integral to membrane active 9734363    
202913 MKK6   pathway input active