Related Signaling interaction pathway:

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FAS signaling pathway (CD95)

Related component ;click for the further info from NCBI
BIDCaspase 8 (cleaved)p15 BIDCaspase 10FASLG
FASFADDFAF1CFLARRIP1
Caspase 3BCL2Caspase 3 (cleaved)GelsolinGelsolin (cleaved)
RFC1 (cleaved)MEKK1ceramidePAK2 (cleaved)Rho GDI beta
Rho GDI beta fragmentRFC1Caspase 7Caspase 7 (cleaved)ICAD
CADICAD (cleaved)MKK4TAK1DNA-PKcs (cleaved)
sphingomyelinalpha Fodrinalpha Fodrin (cleaved)JNK1MEKK1 (cleaved)
NF kappa B1RB1RB1 (cleaved)Lamin A-CCaspase 6 (cleaved)
LAMIN A-C (cleaved)PAK2PARP1PARP1 (cleaved)DNA-PKcs
Caspase 8TOSOIKK alphaCaspase 6IL6
METHGFFAP1

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
202606 BID   modification input cytoplasm   
202570 Caspase 10   modification input 10462485  8524870  9079683  11696979    
202573 FASLG  FAS  FADD  FAF1  Caspase 10   modification input   
202577 Caspase 3   modification input 8663439    
202597 Gelsolin   modification input 9323209    
202601 RFC1 (cleaved)   cell cycle inhibitor   
202585 MEKK1   modification input 15164763    
202581 MEKK1   modification input   
202599 Rho GDI beta   modification input 8626669    
202600 RFC1   modification input 9351817    
202583 Caspase 7   modification input   
202593 ICAD  CAD   modification input   
202603 Caspase 3 (cleaved)   apoptosis input active 8898109  8706867    
202586 MKK4   modification input cytoplasm   
202592 DNA-PKcs (cleaved)   double-strand break repair inhibitor   
202602 sphingomyelin   modification input   
202595 alpha Fodrin   modification input 8940132  9624143    
202587 JNK1   modification input   
202582 MKK4   modification input cytoplasm   
202598 Gelsolin (cleaved)   actin filament polymerization inhibitor   
202584 MEKK1   modification input   
202588 NF kappa B1   modification input 15289496  15843523    
202578 RB1   modification input   
202605 Lamin A-C   modification input 15210759    
202580 PAK2   modification input 11070003    
202579 RB1 (cleaved)   cell cycle inhibitor   
202596 PARP1   modification input   
202591 DNA-PKcs   modification input 8804412    
202607 p15 BID   translocation input cytoplasm   
202575 FASLG  FAS  FADD  FAF1  Caspase 8   modification input 9586636  12215447  11865194    
202589 IKK alpha   modification input   
202604 Caspase 6   modification input 9685181    
202594 CAD   DNA fragmentation during apoptosis agent active   
202590 NF kappa B1   transcription agent active 7543095  15467434    
202572 MKK4   modification input cytoplasm   
202569 FASLG   modification input 11048730  11864613    
202574 FASLG  FAS  FADD  FAF1   modification input   
202608 p15 BID   activation of caspase activity by cytochrome c agent mitochondria   
202571 Caspase 7   modification input 8614469