Related Signaling interaction pathway:

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Signaling events mediated by PTP1B

Related component ;click for the further info from NCBI
STAT5BPTP1Bp62DOKInsulin ReceptorInsulin
JAK2H2O2STAT5ASprouty2Fer
RhoACaT1Src Family KinasesthioredoxinProlactin Receptor
Prolactinp210 bcr-ablGRB2Grb2Jak2
Leptin ReceptorLeptinAKT1SrcPDGFB-D
PDGFRBPTP1B (p42)STAT3 (dimer )SOCS3CAT1
p130 CasCRKCrkTYK2IRS1
PI-3KalphaIIb beta3 Integrinmu-calpainBeta CaseinCSF1
CSF1RYB-1Caveolin-1NOX4NADPH
CskEGFEGFRSTAT3SHC
LATFc gamma RIIaN-cadherin

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
201491 STAT5B   modification input cytoplasm active   
201505 p62DOK   modification input 14766979    
201533 JAK2   modification input active 12748279    
201538 PTP1B   modification input plasma membrane 11864611    
201488 STAT5A   modification input cytoplasm   
201514 PTP1B   modification input 12414790    
201519 PTP1B   modification input 15226396    
201497 PTP1B   modification input 16644720    
201521 CaT1   modification input plasma membrane   
201526 PTP1B   modification input plasma membrane inactive 9624118    
201487 JAK2   modification input 11773439    
201509 p210 bcr-abl   modification input 9566916    
201482 Jak2  Leptin Receptor  Leptin   modification input active 11970899  11694501  11970898    
201480 PTP1B   modification input plasma membrane   
201531 Src   modification input inactive 11346638  15866871  11007774    
201508 PDGFB-D  PDGFRB   modification input active 12424235    
201536 PTP1B (p42)   translocation input plasma membrane   
201484 STAT3 (dimer )   transcription agent active 10514492    
201534 JAK2   negative regulation of transcription agent inactive   
201522 CaT1   modification input plasma membrane active 15894168    
201496 p130 Cas   modification input   
201489 STAT5B   modification input cytoplasm   
201486 TYK2   modification input active 11694501  12748279    
201506 p62DOK   modification input   
201498 PTP1B   modification input plasma membrane 8999839  10807907    
201518 IRS1   modification input active 10660596    
201529 PI-3K   modification input plasma membrane 10751417    
201511 p210 bcr-abl  PTP1B   Ras protein signal transduction inhibitor inactive   
201535 PTP1B   modification input plasma membrane 8223493    
201492 PTP1B   transcription inhibitor plasma membrane   
201507 p62DOK   modification input active   
201515 PTP1B   cell migration inhibitor plasma membrane active   
201537 CSF1  CSF1R   modification input active1 16477024    
201493 p130 Cas   modification input 8940134    
201485 Jak2  Leptin Receptor   modification input 8548812  10514492    
201495 p130 Cas   modification input 9418872    
201513 YB-1   transcription agent 12554649    
201502 Caveolin-1   modification input   
201490 STAT5A   modification input cytoplasm active 10993888    
201527 PTP1B   modification input plasma membrane 14966267    
201530 Src   modification input 1383688    
201503 Caveolin-1   modification input   
201499 PTP1B   modification input plasma membrane 7693694  9355745    
201525 PTP1B   modification input plasma membrane 12802338  9624118    
201483 STAT3   modification input 8782827    
201510 p210 bcr-abl  Grb2   Ras protein signal transduction agent   
201539 Insulin Receptor  Insulin   modification input 8626723  9083103  7983051    
201500 EGF  EGFR   modification input active 9050838  12424235  11900546    
201504 Caveolin-1   modification input active 12176037  16388599    
201512 LAT   modification input 12857726    
201481 Insulin Receptor  Insulin   modification input 11579209  10066179    
201520 PTP1B   modification input plasma membrane active 9786960    
201501 Caveolin-1   modification input 16388599