Related Signaling interaction pathway:

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Canonical NF-kappaB pathway

Related component ;click for the further info from NCBI
I kappa B alphaNF kappa B1 p50RelAIKK complexA20
TNFTNFR1ANEMORIP2NOD2
ELKSBCL10MALT1TRAF6CYLD
IKK alphaIKK betaExportin 1RanGTPATM
PKC alphacIAP1UbcH5CMAP3Ksbeta TrCP1
SCF ubiquitin ligase complex

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
201054 I kappa B alpha   translocation input cytoplasm   
201061 NF kappa B1 p50  RelA  I kappa B alpha   pathway input cytoplasm   
201059 IKK complex   modification input cytoplasm   
201036 NEMO   modification input cytoplasm 15620648    
201042 IKK complex  ELKS   modification input active   
201037 NEMO   modification input cytoplasm 14695475    
201057 NEMO   modification input cytoplasm 12917691    
201038 IKK alpha   modification input cytoplasm   
201056 NF kappa B1 p50  RelA  I kappa B alpha   translocation input nucleus 10688673  11319224    
200539 NF kappa B1 p50  RelA   translocation input cytoplasm active   
201033 NEMO   modification input nucleus 14651848  16497931    
201048 NF kappa B1 p50  RelA  I kappa B alpha   modification input cytoplasm 9150141  9660950  7878466  15218148  7739562  10521409    
201041 IKK complex  ELKS   modification input active 12657630  10195894    
201043 IKK alpha   modification input cytoplasm   
201035 NEMO   modification input cytoplasm 12867425    
201032 NEMO   translocation input cytoplasm 16497931    
201039 IKK complex   modification input cytoplasm active1 15218148    
201058 NEMO   modification input cytoplasm   
201040 IKK complex  ELKS   modification input cytoplasm 9819420  9346241  15218148  16267042    
201052 NF kappa B1 p50  RelA   transcription agent nucleus active   
201062 IKK alpha   pathway input cytoplasm   
201046 IKK alpha   modification input cytoplasm   
201045 IKK alpha   modification input cytoplasm   
201055 I kappa B alpha   modification input nucleus   
201047 IKK complex   modification input cytoplasm 9660950    
201034 NEMO  ATM   modification input nucleus   
201044 IKK alpha   modification input cytoplasm   
201049 NF kappa B1 p50  RelA  I kappa B alpha   modification input cytoplasm active1   
201060 NEMO   modification input cytoplasm 10755617    
201050 I kappa B alpha   proteasomal ubiquitin-dependent protein catabolic process agent cytoplasm inactive