Related Signaling interaction pathway:

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Glypican 1 network

Related component ;click for the further info from NCBI
GPC1PrPcCu2+SLIT2FGF2
FGFR1FGF2 dimerFGFR1 dimerSrc Family KinasesCRIPTO
Src Family Kinases-activeVEGF165 homodimerVEGFR1 homodimerSMAD2ATIII
TGFBTGFBR1TGFBR2APPTGFB family (dimer)
TGFBR2 (dimer)TGFBR1 (dimer)NRGLaminin alpha1PLA2G2A
NRG1SpermineNO

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
200878 GPC1   translocation input plasma membrane 16923158  18717736    
200871 GPC1   modification input plasma membrane 11375980  15063764    
200861 GPC1   modification input plasma membrane 16723715    
200853 Src Family Kinases   modification input cytoplasm 12649175    
200867 GPC1   modification input plasma membrane 10196157    
200859 SMAD2   pathway input cytoplasm active 15249209    
200862 GPC1  FGF2 dimer  FGFR1 dimer   fibroblast growth factor receptor signaling pathway agent integral to membrane active 16723715    
200876 ATIII   modification input 1400362    
200858 SMAD2   modification input plasma membrane inactive 15249209    
200854 Src Family Kinases-active   pathway input cytoplasm 12649175    
200868 APP   modification input extracellular region 15084524    
200855 Src Family Kinases-active   positive regulation of MAPKKK cascade agent cytoplasm 12649175  16123806    
200852 CRIPTO   modification input plasma membrane inactive 12649175    
200869 APP  GPC1   cell death agent plasma membrane active 15084524    
200857 GPC1   modification input plasma membrane 15249209    
200866 GPC1  NRG   neuron differentiation agent plasma membrane active 12914968    
200863 GPC1  FGF2 dimer  FGFR1 dimer   cell growth agent integral to membrane active 16723715    
200874 GPC1   modification input plasma membrane 9949192    
200875 PLA2G2A   modification input extracellular region inactive 10514475    
200865 GPC1   modification input plasma membrane 12914968    
200877 Spermine   translocation input extracellular region 12972423    
200872 GPC1   BMP signaling pathway inhibitor plasma membrane 17516498