Related Signaling interaction pathway:

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IL4-mediated signaling events

Related component ;click for the further info from NCBI
STAT6STAT6 (dimer)IL4IL4RJAK1
IL2R gammaJAK3FESALOX15mTOR
PI3KPI-3-4-5-P3beta3 Integrinp38 alphaSOCS3
FIZZ1IL13RA1JAK2SOCS1IgHG3
SOCS5IL5SP1COL1A2IRS2
IL10SHP1PI-3KIRS1STAT6 (cleaved dimer)
CCL17CEBPBIgHG4STAT5STAT5 (dimer)-active
SHIPPSELSPI1ARG1BCL-XL
OPRM1AKT1BCL6HMGIYIgE
GTF3ACOL1A1SHCGRB2AID
PARP14EGR2IRF4FCER2TNFB
ETS1CBLDOK2a-cMybCCL11
IL13RA2CD40LGPI-4-5-P2THY1TFF3
p70S6KMHC II antigensCCL26PIGR

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
200707 STAT6   modification input cytoplasm active 9651359  17200144    
200746 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 11160325    
200734 STAT6 (dimer)   transcription agent nucleus active 10657944    
200754 mTOR   modification input 10843732    
200732 STAT6 (dimer)   transcription agent nucleus active 11241672    
200765 p38 alpha   transcription agent active 15728454    
200729 STAT6 (dimer)   transcription agent nucleus active 12574343    
200704 IL4  IL4R  JAK1   modification input integral to membrane 9013879  7721786  10950967  8992992  10201892  8609418    
200764 p38 alpha   modification input 15728454    
200728 STAT6 (dimer)   transcription agent nucleus active 10228008    
200763 IL4  IL4R  JAK1   modification input integral to membrane 8624802  7822337  12242343  9799097  8134361  9380721  8458387  12459556  1948049  7973658    
200719 STAT6 (dimer)   transcription agent nucleus active 8602264  8602263  8624821    
200739 STAT6 (dimer)   transcription agent nucleus active 14603527    
200747 IL4  IL4R  JAK1  IL2R gamma  JAK3  FES   modification input integral to membrane active 11160325  7499365  7675087    
200769 STAT6 (dimer)   T-helper 1 cell differentiation inhibitor nucleus active   
200720 STAT6 (dimer)   transcription agent nucleus active 8602264  8602263    
200714 PI3K   modification input plasma membrane active 9065461    
200703 IL4  IL4R  JAK1   modification input integral to membrane 8624802  7822337  9799097  8134361  9380721  10950967  10201892  8458387  12459556  1948049  7973658    
200749 PI-3K   modification input plasma membrane 7499365  7675087    
200742 STAT6 (dimer)   modification input nucleus active 10072514    
200745 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 8124718  7499365    
200766 STAT6 (dimer)   transcription agent nucleus active 16810739    
200710 STAT6 (dimer)   transcription agent nucleus active 8089482  1997653  8602263  8258319  7694370    
200767 STAT5   modification input cytoplasm 11160275    
200713 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 9670964  11714803    
200733 STAT6 (dimer)   transcription agent nucleus active 10364072    
200735 STAT6 (dimer)   transcription agent nucleus active 15187136  11160269    
200768 mTOR   mitosis agent active 16210622    
200743 STAT6 (dimer)   transcription agent nucleus active 12023955    
200737 STAT6 (dimer)   transcription agent nucleus active 11572871    
200756 AKT1   modification input cytoplasm 14557412    
200712 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 9065461  11714803    
200711 STAT6 (dimer)   transcription agent nucleus active 10490661  7807002  7705411  1997653  8602263  15659391  8602264  8258319  8624821    
200740 STAT6 (dimer)   transcription agent nucleus active 14603527    
200751 IL4  IL4R  JAK1  IL2R gamma  JAK3  FES  IRS2   T cell proliferation agent integral to membrane active 14557412  11160325  11739727    
200760 IL4  IL4R  JAK1  IL2R gamma  JAK3  SHC  SHIP  GRB2   MAPKKK cascade agent integral to membrane active 8621475    
200705 STAT6   modification input cytoplasm 8085155  11714803  7544011  8602264  15153491  9852037  12459556  7760829    
200770 STAT6 (dimer)   transcription agent nucleus active 14978013    
200706 STAT6   modification input cytoplasm 8609418  8085155    
200709 STAT6 (dimer)  PARP14   transcription agent nucleus active 11801631  10601358  8624803  8602263  7694370  16537510    
200752 STAT6 (dimer)   T cell proliferation agent nucleus active 11739727    
200731 STAT6 (dimer)   transcription agent nucleus active 9541585    
200730 STAT6 (dimer)  ETS1   transcription agent nucleus active 14634100  15199062    
200758 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 8557643  8621475    
200761 CBL   modification input cytoplasm 9414268    
200757 IL4  IL4R  JAK1  IL2R gamma  JAK3   modification input integral to membrane active 9697832    
200744 STAT6 (dimer)   transcription agent nucleus active 8602264  7807002  1997653  12044779  8602263  8258319  8624821    
200725 STAT6 (dimer)   transcription agent nucleus active 10586089  17541284    
200736 STAT6 (dimer)   transcription agent nucleus active 12776189    
200724 IL4  IL4R  JAK1  IL2R gamma  JAK3   transcription agent integral to membrane active 10601358    
200759 IL4  IL4R  JAK1  IL2R gamma  JAK3  SHC  SHIP   modification input integral to membrane active 8621475    
200721 STAT6 (dimer)   transcription agent nucleus active 11801631    
200753 PI-4-5-P2   modification input plasma membrane   
200722 STAT6 (dimer)   transcription agent nucleus active 8602264    
200723 STAT6 (dimer)   modification input nucleus active 15199062    
200715 BCL6   T-helper 2 cell differentiation inhibitor 8602264  2147202  9811885  9110977  11739727  8624821    
200741 STAT6 (dimer)   transcription agent nucleus active 15004182    
200755 p70S6K   modification input cytoplasm 11160325    
200716 STAT6 (dimer)   transcription agent nucleus active 8602264  8602263  8624821  3144043    
200750 PI-3K   modification input plasma membrane 8916957  11160325  7675087  11739727    
200702 IL4   modification input extracellular region 8266078  8266076    
200762 PI-3K   modification input plasma membrane 9414268    
200718 STAT6 (dimer)   transcription agent nucleus active 8602264  8602263  8624821  10072514    
200727 STAT6 (dimer)   transcription agent nucleus active 11544308    
200738 STAT6 (dimer)   transcription agent nucleus active 11034397    
200717 STAT6 (dimer)   transcription agent nucleus active 8810328  8624821    
200708 STAT6 (dimer)   translocation input cytoplasm active 8085155