Related Signaling interaction pathway:

Data buffering takes about 1 or more minute acording to the network size.



S1P1 pathway

Related component ;click for the further info from NCBI
S1P1S1PGiPDGFB-DPDGFRB
SphingosineSPHK1PLCgamma1VEGFR2 homodimerVEGFA homodimer
Gi familyERK1-2-activeCOX-2PLC beta 2ABCC1
RhoAGDPGTPRAC1Rac1
alphaVbeta3 IntegrinPKCERK1-2

Related interaction Related unit Interaction type Unit type Subcellular localization Activity state Related Article
202753 S1P1  S1P   receptor internalization agent active 10198065  11741892    
202739 S1P1  S1P  Gi   negative regulation of cAMP metabolic process agent active 9660876    
202735 S1P   modification input extracellular region   
202736 S1P1  S1P   modification input active 11709084    
202733 Sphingosine   modification input   
202743 PLCgamma1   modification input cytoplasm   
202737 S1P1  S1P  PDGFB-D  PDGFRB   pathway input plasma membrane active   
202745 S1P1  S1P  Gi   negative regulation of T cell proliferation agent active 12586615    
202750 VEGFR2 homodimer  VEGFA homodimer   transcription agent plasma membrane active 12963813    
202738 S1P1  S1P   modification input active 9660876    
202742 ERK1-2-active   transcription agent active 12796504    
202755 PLC beta 2   modification input   
202734 S1P   translocation input cytoplasm 17050692    
202760 RhoA  GDP   modification input inactive 11150298    
202759 RAC1  GDP   modification input inactive 11150298  17257496    
202731 PDGFB-D  PDGFRB   modification input plasma membrane active 10463951    
201607 alphaV  beta3 Integrin   endothelial cell migration input 11150298    
202732 SPHK1   modification input cytoplasm 10463951    
202757 S1P1   modification input 12087059  15750791    
202752 S1P1  S1P   modification input active 12782628  11741892    
202741 ERK1-2   modification input 12175535